COVID-19 Vaccine Mainly Pray Mainly because Taught Treatment plans Cannot Clearly show Outcome?
January 13, 2021 Health
Even with almost annually of its worldwide invasion the SARS-Cov-2 virus called COVID-19 continues to take pleasure from an edge over humankind which can be not surprising thinking about the unprecedented crisis earned by a disease hardly recognized to anybody, its seemingly selective approach when it comes to mildness or severity of the infection, baffling all medical scientists and doctors. Humankind, in its present very advanced stage of the information search, is never a party to just accept defeat, and therefore, the quest has been relentlessly going on all over for a powerful vaccine, and meanwhile intent research on anti-viral or anti-malarial repurposed drugs, plasma therapy and other possible methods of treatment. The principal interest of efforts staying at least to cut back the mortality rates which also differ country-wise and inexplicably, and till today it has been an accepted fact that there’s no cure for the disease. Various vaccine projects in a variety of stages of development have been in full swing in a variety of countries with a lot of them promising a vaccine by the newest year day or early next year. Now, the newest disappointing developments on treatment methods practiced so far have posed probably the most relevant question: is a powerful vaccine only a cure for humankind?
Most of us remember the desperate international craving for a basically Indian anti-malarial drug called Hydroxychloroquine (HCQ) once the pandemic was raging furiously in Europe and the US, and the US President likely to the extent of threatening India if supplies of HCQ were not. However, slowly as time passes this drug was found ineffective and somewhat harmful too according to natural immunity โควิด 19. Then there have been some other drugs and steroids that were combined with seemingly hopeful results, Remdesivir being usually the one most welcomed one as a life-saver.
The outcome of the Solidarity Clinical Trial, one of many largest international Randomized Controlled Trials (RCT), that’s been conducted by the World Health Organization (WHO) since March 2020 were declared recently which marked four of the very promising drugs as ineffective in reducing mortality. The four evaluated treatment methods, HCQ, Remdesivir, Lopinavir or Ritonavir and Interferon, have now been found to possess little or no affect mortality rates. As far as the RCTs conducted in a variety of countries of the world including in China are involved there have been doubts on their findings, and experts wish for more such studies. Objections were raised from the Solidarity Trial too as regards to its sampling methodology from various quarters, with one Indian hospital refusing to stop using Remdesivir claiming its benefits within the months inside their patients. However, technically, it means that aside from Corticosteroids that have been proven effective in treating critical patients there’s no other deemed treatment method, and in addition it must be remembered that steroids aren’t recommended for less-severe or general patients.
More disappointing news came next from the Indian Council of Medical Research (ICMR) on the efficacy of the Convalescent Plasma Therapy (CPT), so far permitted being an investigational therapy in progressive stages of the illness in India, which involves taking out blood plasma from recovered COVID-19 patients and injecting this antibody-rich extract into positive patients, specially the more severe ones treated in hospitals. Within the months it has been progressed into a systematic treatment method creating proper channels of donations throughout the states as infected doctors too caused it to be a point out donate the precious plasma.
The Director General of the ICMR declared the results on 20th October 2020 after conducting its RCT during April-July period of the season covering over 400 hospitals across 39 medical centers of the country. On the basis of the results the ICMR has figured the CPT fails to cut back the mortality rates or prevent the progression of COVID-19 infections from moderate to severe stages. Following this choosing the Government of India is mulling removal of CPT from its COVID-19 protocol for national clinical management. This is indeed sad news as CPT is a remarkably popular way of COVID-19 treatment in the lack of a powerful vaccine.
Experts, however, aren’t convinced concerning the CPT results saying that it might experienced to do with the delay of the infusion and the grade of the antibodies. Internationally, the CPT continues to be remedy method meant just for emergency use. Anyway, because of these findings the importance of discovering a powerful vaccine grows even more. The pandemic is far from keeping its clutches off humankind yet: after over half a year of haphazard acceleration India has finally reached its peak in the third week of September 2020 with new cases still hovering around fifty thousand each day and 500+ daily deaths as the European countries and the US are experiencing a second wave.
Chinmay Chakravarty is a professional specialized in the creative field with over 2 decades of experience in journalistic writing, media co-ordination, film script writing, film dubbing, film & video making, management of international film festivals and editing of books & journals. Proficient in providing professional services in these related fields. Was an officer of Indian Information Service and superannuated from the post of Director, Press Information Bureau, Kolkata in November, 2019. Published his first solo book’Laugh and Let Laugh’in 2017.